Back to Results
Meet Michael D. House, MD
Title(s)
Program Director, Maternal Fetal Medicine Fellowship; Professor, Tufts University School of Medicine
Department + Services
Obstetrics and Gynecology, Maternal-Fetal Medicine (High-Risk Pregnancy)
Clinical Focus Areas
High-risk pregnancy, biomechanics, ultrasound
Seeing Patients In
Boston, 617-636-4549
Request Appointment
| Programs + Specialties |
|
| Training + Education |
University of Southern California; Tufts Medical Center; Los Angeles County, University of Southern California Women and Children's Hospital
|
| Board Certifications |
Maternal-Fetal Medicine, Obstetrics and Gynecology |
| NPI # |
1851405740 |
| Gender |
Male |
| Accepted Insurances |
View Accepted Insurances at Tufts Medical Center
|
Tufts Medical Center
South Building, 2nd Floor
800 Washington St.
Box 360
Boston, MA 02111
Phone #: 617-636-4549
Fax #: 617-636-4202
|
2023, Keynote Lecturer, International Symposium on Computer Methods in Biomechanics and Biomedical Engineering (CMBBE), Paris, France
2021, Appointed Member, Intramural - Extramural Collaboration for Drug Screening with Biofabricated 3-D Disease Tissue Models (UH2/UH3) NIH Study Section
2020, Appointed to the Board of the Perinatal Quality Foundation (ex-officio)
2016-2021, "Top Doctor," Boston Magazine
2013, Elected President of New England Perinatal Research Society
2012, Elected Vice-President of New England Perinatal Research Society
2012, Award for Best Poster at 32nd Annual Meeting, SMFM
2008, Elected member, Perinatal Research Society
2007, Reproductive Scientist Development Program, K12 Award, NICHD
2006, Best Oral Presentation at SMFM
2005, Best Oral Presentation at SMFM
2002, AAAOGF - SMFM Scholarship Award
For a complete list of Dr. House's publications, see here: Full list
SELECTED NATIONAL PRESENTATIONS
"The Cervix as a Biomechanical Structure," Women's Health Engineering Seminar, Washington State University, September 22, 2022.
NICHD R41HD102268
Small Business Technology Transfer (STTR) Program
2020-2021
A Novel Device for Cervical Insufficiency in Pregnant Women
This STTR will develop an innovative medical device to treat cervical insufficiency with improved efficacy and fewer complications compared with traditional cerclage.
Role: PI
M2D2 Grand Prize Award
2020
Massachusetts Life Sciences Center
Massachusetts Medical Device Development Center
The goal is to assist Cx Therapeutics in Developing an Innovative Medical Device to Treat Cervical Insufficiency Compared with Traditional Cerclage.
COVID-19 Rapid Response Seed Funding Grant
2020-2021
Reducing the stress associated with performing non-stress tests – evaluating potential acceptance for home-based monitoring.
The study aims to gather information that can inform how to approach home-based non-stress tests; the likelihood that a test would result in a patient needing clinical care acutely via a retrospective chart review and the perspective of patients who would potentially undergo home-based testing with a prospective survey.
Role: PI
SMFM/ABOG Bridge Grant
2020-2021
Novel tools for studying cervical function and dysfunction during pregnancy.
The goal of the project is to gain critical insights into mechanisms of preterm birth where cervical dysfunction is the cause.
Role: Principal Investigator
NIH 1R01HD084695-01A1
2016-2021
“Mechanisms of Infection-Mediated Cervical Ripening.”
The goal of this project is to acquire a greater mechanistic understanding of biochemical pathways leading to cervical ripening, with a particular emphasis on infection-mediated cervical ripening.
Role: Co-Principal Investigator
MIT: Burroughs Wellcome Fund
Sub Award #5710003419 2013-2017
Properties and Functions of Cervical Mucus Associated with Preterm Birth
The goal is to increase understanding of the basic biological mechanisms underlying parturition and spontaneous birth using multidisciplinary approaches.
Role: TMC Principal Investigator
5R01HD091153-04
NICHD
2017-2022
A computational framework for the clinical evaluation of the soft tissue mechanics in pregnancy to understand what causes the mechanical dysfunction in pregnancy, a finite element (FE) simulation framework will be built to identify the anatomical and/or material factors that drive uterine, cervical, and fetal membrane tissue remodeling and deformation.
Role: Consultant
NICHD Scholar of the RSDP
K12HD000849 2007-2013
Cervical Tissue Engineering for Studying Obstetrical Biomechanics.
The goal is to use a tissue engineering strategy to study mechanisms of cervical remodeling during pregnancy.
Role: Principal Investigator
Burroughs Wellcome Fund – Preterm Birth Initiative
2009-2010
Beyond Cervical Length: Development of a Patient-Specific Model of Cervical Mechanical Function during Pregnancy.
The goal of this study was to determine biomechanical function of the cervix during pregnancy by combining three-dimensional ultrasound with biomechanical models of cervical mechanics.
Role: Principal Investigator
Dr. House's research focus is on studying the role of the cervix in normal and high-risk pregnancy. Normal cervical function is critical for a healthy pregnancy but premature cervical shortening and dilation is associated with preterm birth, which affects 12% of pregnancies in the United States. Research activities include 1) design and evaluation of three-dimensional models of cervical tissue to study remodeling of the cervical extracellular matrix, 2) investigation of the cervical biomechanical function using mechanical modeling techniques, 3) study of the barrier properties of cervical mucus as it relates to protection against intrauterine infection and 4) development of novel therapies such as injectable biomaterials to augment cervical function during pregnancy. This research is valuable for understanding why the cervix stays closed in normal pregnancy but shortens and opens in preterm birth. Successful accomplishment of this research relies on a collaborative multidisciplinary research team involving investigators with expertise in mechanical engineering, biology and maternal fetal medicine.
